1、The company's mismanagement led to ruinously high debt levels.
该公司的管理不善导致债务水平高得令人难以承受。

2、The decision to invest all his savings in a risky venture proved to be ruinously unwise.
把他所有的储蓄都投资到一个风险高的企业是一个毁灭性的不明智决定。